A Vitamin Success Story: Healthier Babies From Folic Acid Fortification
A new systematic review published online today in Public Health Nutrition by Castillo-Lancellotti, Tur and Uauy reviews the effects of folic acid fortification on rates of neural tube defects in 9 countries located in Africa, North America, South America and the Middle East. Folic acid is one of the B-vitamins. It is involved with amino acid metabolism, DNA synthesis and red blood cell production. Developing embryos undergo rapid rates of cell division, and it is thought that folic acid deficiency impairs the closure of the neural tube around week 6 of pregnancy. The abnormal opening in the neural tube is called a neural tube defect (NTD), which occurs in roughly 2 to 10 births per 10,000 births. NTDs are often very serious conditions, resulting in growth retardation, paralysis, increased risk of infection, mental retardation and death in the fetus or infant. Read more